Egl nine homolog 2 (EGLN2) polyclonal antibody

$175.00
SKU:
ABP-PAB-11634
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[[100 µg, ABP-PAB-11634]]

Hypoxia-inducible factor (HIF), a transcriptional complex conserved from Caenorhabditis elegans to vertebrates, plays a pivotal role in cellular adaptation to low oxygen availability.In normoxia, the HIF-alpha subunits are targeted for destruction by prolyl hydroxylation, a specific modification that provides recognition for the E3 ubiquitin ligase complex containing the von Hippel-Lindau tumour suppressor protein (pVHL).

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