[[100 µg, ABP-PAB-11165]]
(100 µg) Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor (EGFR) and the adaptor protein Shc are substrates protein tyrosine phosphatase non-receptor type 2 (PTPN2), which plays an important role in growth factor-mediated cell signaling. Amino acids 369 - 382.