Immunogen:
KLH conjugated synthetic peptide comprised of amino acids 409 - 424 [RFDENSQSMEQGFPRC] of the human matrix metalloproteinase 10 (MMP10) protein. 

Accession number:
NM_002425

Description:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. Matrix metalloproteinase 10 (MMP10) ) degrades proteoglycans and fibronectin.

Alternative Name(s):
matrix metalloproteinase 10, SL-2, STMY2, transin 2, stromelysin 2, MMP10 

1. Nagase H, Woessner JF Jr.: Matrix metalloproteinases. J. Biol. Chem. 274(31): 21491-21494 (1999).
2. Sirum KL, Brinckerhoff CE: Cloning of the genes for human stromelysin and stromelysin 2: differential expression in rheumatoid synovial fibroblasts. Biochemistry 28(22): 8691-8698 (1989).

For Research Use Only. Not for Diagnostic or Therapeutic Use.

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