Continued Expansion of Off-the-Shelf cGMP iPSC Line Library
The Allele iPSC division has dedicated capacity to steadily expand its off-the-shelf cGMP iPSC line offerings. Every quarter, we initiate reprogramming of cells from two new donors and obtain three entirely independent iPSC lines from each donor. At the current pace, Allele’s cGMP iPSC line library grows by six lines every three months, which can be adjusted to align with market demand. This commitment aims to ensure that Allele provides licensees and partners with opportunities to compare multiple lines if so desired before embarking on a lengthy and costly product development journey.
Streamlining Your Path: Accessing, Testing, and Licensing
Our partner process begins with a testing phase, during which you can access Allele’s off-the-shelf cGMP iPSC line library and test multiple lines for iPSC maintenance, expansion, and differentiation based on your product’s specific design and workflow. In some cases, the licensee prefers to include additional testing in animal models to further consolidate their pre-clinical proof-of-concept results for their investors.
From there, we move forward to the development of a customized licensing agreement tailored to your specific needs. This agreement can be adapted to include exclusivity in a designated cell line, application fields or indications, and market territories. Considerations can be made in line with the preferred balance of upfront payments, milestones, and royalties.